Pathology and Current Treatment of the Alzheimers Disease Essay

Pathology and Current Treatment of the Alzheimer's Disease Introduction One of the most feared aspects of aging is the deterioration of the memory and cognitive function (dementia) that occurs among the elderly with increasing frequency with advancing years. A significant proportion of otherwise healthy elderly persons show a significant decline in mental function later in life. It has been estimated that 10% of the population over the age of 65 suffers from mild to moderate dementia and 4-5% suffer from severe dementia. The incidence of severe dementia rises from less than 1% at ages 65 to 70 to over 15% by age 85 (Terry and Katzman, 1983). In the United States alone, Alzheimer’s disease (AD), which is the major cause of senile dementia, afflicts several million people, and with the increasing longevity of the population, the number of such patients requiring complete and continuous institutional care will rise to epidemic proportions. This paper will attempt to describe the Alzheimer's Disease condition, both behaviorally and neuropathologically , and then look at traditional and current methods of treatment for patients of Alzheimer's Disease. The onset of senile dementia is characterized by increasing impairment of memory of recent events such as what a patient had for breakfast an hour earlier, though a detailed recall of the distant past may be essentially intact. Inevitably, the patients lose their cognitive abilities, that is, their abilities to read, write, calculate, and use language appropriately; they cannot feed or dress themselves, they do not recognize their own families, they get lost when only a short distance from home, and ultimately do not even know their own names (R. Perry et al., 2000, C.J.A. Mouli... ...minimal and mild) Alzheimer's Disease: relationship to episodic and semantic memory impairment, Neuropsychologia, 38:3, 2000, p. 252-271 Prasad, K.N., Hovland, A.R., Cole, W.C., Prasad, K.C., Nahreini, P., Edwards-Prasad, J., Andreatta, C.P. Multiple antioxidants in the prevention and treatment of Alzheimer's Disease: Analysis of biochemical rationale, Clinical Neuropharmacology, 23:1, 2000, p. 2-13 Roses, A.D. Apolipoprotein E affects the rate of Alzheimer's Disease expression: b -amyloid burden is a secondary consequence dependent on apoE genotype and duration of disease, J. Neuropathol. Exp. Neurol, 53, 1994, p. 429-437 Terry, R.D., Katzman, R. Senile dementia of the Alzheimer’s type, Ann. Neurol., 14, 1983, p. 497-506 van Leuven, F. Single and multiple transgenic mice as models for Alzheimer's Disease, Progress in Neurobiology, 61:3, 2000, p. 305-312

The Welcome Table by Alice Walker

I choose to analyze The Welcome Table by Alice Walker; this story is about an old, rundown black woman who staggers the necessary distance in the freezing cold to attend an all-white people church. The Welcome Table is told in the third person and shifts the point of view from which the story is told. The white people are at a loss when they see her near the entrance of the church and do not know what to do. Some people take her in as she is, an old black woman with a mildewed dress that is missing buttons. She is lean and wrinkled with blue-brown eyes. Her appearance makes some of the white people think of black workers, maids, cooks; others think of black mistresses or jungle orgies. Still others think that she is a foreshadow of what is to come – black people invading the one place that it still considered the white person's sanctuary, their church. They see her and transfer their fear of blacks onto her. The beginning of the story is told from the white people's perspectives as they see an old black woman come to their church and go inside. Inside the church, the point of view switches to the usher who tells the old black lady to leave. The point of view then switches back to the white women inside the church, who take it as a personal insult and feel the most threatened about the old black lady being at their church. They rouse their husbands to throw the old lady out. The perspective then changes to the old black lady. This constant changing of point of view is useful in that it portrays the fears, thoughts, and feelings of almost everyone in the story. Firsthand, the reader is able to know what the people are thinking and why. In the end, the point of view briefly returns to the white people who were at church that day. The story ends with the perspective of some black families who witnessed the old lady walking down the highway. The story starts on a Sunday morning at the steps of the church that white people attend. The focus moves briefly inside the church where it is cold. As the story progresses the setting moves to the highway located outside the church. It is freezing outside. It is interesting to note that the old black woman does not find Jesus inside the â€Å"white† church but outside of it. Also of interest; prior to meeting Jesus, the old black woman is cold and shivering. After meeting Jesus, no mention is made of the woman's being cold or shivering. Walker does not give a specific time period in which the story takes place or a specific location. This might have been done to make the story timeless. The language used in The Welcome Table is very descriptive in her details of the old black woman's appearance and the appearance of Jesus. Walker is also detailed when describing the white people's different emotions, thoughts, and feelings. Walker provides insight into all the characters with her word choices, and by doing so, makes a simple story more profound. Walker writes this story straight through for the most part with only two breaks. The first break comes immediately after the old woman is thrown out of the church. The point of view then shifts to the old black woman whose thoughts and feelings were unknown to the reader up to this point. The second break occurs after the old woman is walking with Jesus. Walker uses the break to shift forward in time in the white people's perspective. Although the old woman dies at the end of the story and an argument could be made that she was walking alone, this story contains hope and leaves the reader with a good feeling. The story gives hope that people who have lived a life of servitude and poor treatment will, in the end, find kindness, acceptance, and joy.

The Problems Of Integration Of Immigrants - 1300 Words

The problems of integration of Immigrants in Canada: What problems did the high skilled immigrant s faces? Introduction Even though the Canada is historically was settled and developed by immigrants, the immigration and integration of migrants are still controversial issues in Canada. Integration is also a multidimensional process involving economic, social, political, and cultural integration. Unfortunately, current immigration policies in Canada’s new economy have primarily focused on economic integration with an emphasis on the economic interests of the state. Political integration has also been narrowly limited to voting during election time. Policies largely ignore social and cultural integration of immigrants as they try to†¦show more content†¦Sometimes it is used interchangeably with adjustment, adaptation, and acculturation. Very often it is treated as a process as well as an outcome, an individual and a group phenomenon, and a change in attitudes as well as behaviors. Shibao Guo and Yan Guo point out that in other cases it is portrayed as an â€Å"alternative to ‘assi milation,’ a more negatively-connoted term that describes a one-way process wherein immigrants abandon their previous cultures and adapt to their new society.† Immigrants need to integrate into Canadian society whether people portray positively or negatively. When Canada was primarily an agricultural nation, immigrants were sought to populate rural lands across the country. Then, as industrial development accelerated in the twentieth century, immigrants were needed to meet needs in urban factory work and construction. More recently, as Canada has moved toward a post-industrial service economy or the ‘knowledge economy,’ immigration has emphasized labor demand for skilled workers, as reflected in the 1967 introduction of the ‘points system’ for selecting immigrants on the basis of education and occupational skills. 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